TEG Vapor Study Reports

Below are the full study reports we've compiled related to the use of Triethylene and Propylene Glycol vapors (theatrical fog) as a disinfectant against viral, bacterial, and fungal microbes, arranged chronologically. Items in red are yet to be located in full. We will update the list as new documents are obtained. Click on the item numbers next to the references to view the full documents. 

There are a lot of documents to absorb here, so a good way to become oriented is with the Excerpts page.

Of particular interest is document #22 produced by the FAA in 2009 regarding disinfecting airplanes.

Also of summary interest are documents #14, 15, & 17.

Toward the bottom of the list are more recent documents, including reports by the FDA, NIH, & EPA and a new report published this month regarding the airborne suspension of speech droplets - document #36.

And finally, if you have questions or additional studies or information to contribute, please email us at info@asepo.org.

The Reports and Related Data                      PDF Version HERE

1 - Sterilization of air with glycol vapors. Robertson, O.H., Harvey Lecture Series. 1942–1943; 38: 227-234

2  - The bactericidal action of propylene glycol vapor on microorganisms suspended In air. II. The influence of various factors on the activity of the vapor. Puck TT, Robertson OH, Lemon HM.. J Exp Med. 1943;78:387–406. PMID:19871337.

2.5 - The Lethal Effect of Triethylene Glycol Vapor on Airborne Bacteria and Influenza VirusRobertson, O.H., Puck, T.T., Lemon, H.M., Loosli, C.G., Science, 97:142-144, (Feb) 1943

3 - Engineering Problems in the Use of Glycol Vapors for Air Sterilization. Jennings, B. H., and Bigg, E. A.J.P.H., 34:477 (June), 1944

4 - A Device For Automatically Controlling the Concentration of Glycol Vapors in the Air, Puck, T.T., Wise, H., Robertson, O.H., J. Exp. Med., 1944, 80:377-381.

5 - Summary of a 3-Year Study of the Clinical Applications of the Disinfection of Air by Glycol Vapors. Harris, T.N., Stokes, J., Jr. Am. J. Med. Sc., 209:152-156, (Feb) 1945 (abstract only)

6 - Epidemiologic Observations on the Use of Glycol Vapors for Air Sterilization. Bigg, E., Jennings, B.H., Olsen, F.C.W. A.J.P.H. 35:789, 1945

7 - Control of cross infections in infants' wards by the use of triethylene glycol vapor. Loosli, C.G., Smith, M.H.D., Gauld, R., Robertson, O.H., Puck, T.T. Am. J. Pub. Health. 1947; 37: 1385-1398

8 - New methods for the control of air-borne infection with especial reference to the use of triethylene glycol vapor. Robertson, O.H., Wisconsin M. J.  (March) 1947; 46: 311-317 (abstract article only)

9 - Disinfection of Clouds of Meningopneumonitis and Psittacosis Viruses with Triethylene Glycol Vapor.  Rosebury, T., Meiklejohn, G.,  Kingsland, L.C., Boldt, M.H. J. Exper. Med. 1947; 85: 65-76

10 - Saturation concentrations of triethylene glycol vapor at various relative humidities and temperatures. Wise, H., Puck, T.T., Science. 1947; 105: 556-557 (Page 1 only)

11 - Glycol Vapors for Disinfecting Purposes, Editorial Journal of the American Medical Association, 133:696, March 8, 1947)

12 - An automatic dewpoint meter for the determination of condensable vapors Puck, T.T.,. Rev. Scient. Instruments. 1948; 19: 16-23

13 - The rate of bactericidal action of triethylene glycol vapor on microorganisms dispersed into the air in small droplets. Lester, W.,Jr., O.H. Robertson, T.T. Puck, and H. Wise. 1949. Am. J. Hyg. 50:175-188.

14 – Glycol Vapors for Disinfection Purposes. Bulletin of U.S. Army Medical Department, Vol.IX, No7: July 1949 :542-548

15 - Disinfection of the Air with Triethylene Glycol Vapor Robertson, O.H.. Am J Med, 7(3):293-296, 31 Aug 1949

16 - Commercial exploitation of glycol vaporizers. Am. J. Pub. Health. 1949; 39: 222-224

17 - Factors of Importance in the Use of Triethylene Glycol Vapor for Aerial Disinfection. Lester, W., and Kaye, S. A.J.P.H., 40:813 (July), 1950

17.5 - Effect of Propylene and Triethylene Glycol on Atomized E. coli, Nagy, R., Mouromseff, N.,  Science  112:2916 p.593-595, (Nov) 1950

18 - Physical aspects of air disinfection. Nash, T. J. Hyg. 49, 382–399 (1951).

19 - Air sterilization in an infants' ward; effect of triethylene glycol vapor and dust-suppressive measures on respiratory cross infection rate. Krugman S, Ward R. J Am Med Assoc. 1951 Mar 17;145(11):775–780.

20 - The Use of Triethylene Glycol Vapor for Control of Acute Respiratory Diseases in Navy Recruits, II. Effect on Acute Respiratory Diseases, Personnel of United States Naval Medical Research Unit No. 4.  Am J Hyg 55: 215-229, 1952.

21 - Efficacy Data and Labeling Requirements: Air Sanitizers, EPA, DIS/TSS-11 / https://www.epa.gov/pesticide-registration/efficacy-data-and-labeling-requirements-air-sanitizers, Sep. 3, 1980

21.5 - Reregistration Eligibility Decision (RED) for Triethylene Glycol, EPA, List C, CASE 3164 (Sep) 2005

22 - Inactivating Influenza Viruses on Surfaces Using Hydrogen Peroxide or Triethylene Glycol at Low Vapor Concentrations Stephen N. Rudnick, James J. McDevitt, Melvin W. First, John D. Spengler. Am J Infect Control. 2009 Dec; 37(10): 813–819. Published online 2009 Oct 12. doi: 10.1016/j.ajic.2009.06.007 funded by the USDOT and FAA Office of Aerospace Medicine

23 - Anti-influenza virus activity of essential oils and vapors, Selvarani Vimalanathan, James Hudson. AJEONP 2014; 2 (1): 47-53

24 - Resistance of Aerosolized Bacterial Viruses to Four Germicidal Products  Nathalie Turgeon, Kevin Michel, Thi-Lan Ha, Enric Robine, Sylvain Moineau, Caroline Duchaine  https://doi.org/10.1371/journal.pone.0168815

(Dec) 2016

25 - Report of Findings - Recommended Exposure Guidelines for Glycol Fogging Agents, Entertaiment Services Technology Association, The Cohen Group, Proj. No. 6070-1001, (Feb) 1997

25.2 - Development of Calibration Factors for Monitoring Theatrical Smoke and HazeEntertaiment Services Technology Association, Environ, (Nov) 2002

25.3 Theatrical Fog Made With Aqueous Solutions of Di- And Trihydric Alcohols. Entertaiment Services Technology Association, Entertainment Technology - ANSI E1.5-2003 (R2009)

25.4Theatrical Fog Made With Aqueous Solutions of Di- And Trihydric Alcohols. Entertaiment Services Technology Association, Entertainment Technology - ANSI E1.5-2009 (R2018)

26 - Decontaminating surfaces with atomized disinfectants generated by a novel thickness-mode lithium niobate device, Monika Kumaraswamy, Sean Collignon, Carter Do, Janie Kim, Victor Nizet, James Friend. . Applied Microbiology and Biotechnology, 2018; 102 (15): 6459 DOI: 10.1007/s00253-018-9088-0

27 - Training Smoke Uses Resources to Tackle COVID-19, Fire Engineering, https://www.fireengineering.com/2020/03/30/486012/training-smoke-uses-resources-to-tackle-covid-19/#gref, (Mar) 2020

28 - Triethylene Glycol, Wikipedia, Text is available under the Creative Commons Attribution-ShareAlike License, (Apr) 2020

29 - List N: Disinfectants for Use Against SARS-CoV-2, EPA, https://www.epa.gov/pesticide-registration/list-n-disinfectants-use-against-sars-cov-2, (Apr) 2020

30 - COVID-19 Doesn’t Like Look Solutions Fog & HazeLook Solutions, https://looksolutionsusa.com/covid-19-doesnt-like-look-solutions-fog-haze/, (Mar) 2020

31 - Look Solutions TEG/PG Fog Juice - Safety Data Sheet

32 - Look Solutions Fog Machines - Fluid Consumption Table, Look Solutions

33 – Fog Information for Nervous Actors, Look Solutions

34 - Compound Summary of Triethylene Glycol, NIH, Nat'l Lib. of Med., Pub Chem ID 8172, (May) 2020

35 - Table Z-1 Limits for Air Contaminants, OSHA eCFR, Title 29, Vol. 6. Ch. XVII, 1910-1000, Subpart Z, 2020

36 - The Airborne Lifetime of Small Speech Droplets and Their Potential importance in SARS-CoV-2 Transmission, Stadnytskyi, V., Bax, C., Bax, A., Anfinrud, P., PNAShttps://doi.org/10.1073/pnas.2006874117, (May) 2020

** Also, many official reports on the use of glycol vapor "fog"

for theatrical purposes can be found at:


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